Your browser doesn't support javascript.
loading
Clinico-pathological presentation and therapeutic options for hairy cell leukemia
JPMI-Journal of Postgraduate Medical Institute. 2012; 26 (3): 336-339
in English | IMEMR | ID: emr-144373
ABSTRACT
To look at clinical and hematological presentation as well as treatment outcome of patients with diagnosis of Hairy Cell Leukemia [HCL] in our population. All patients diagnosed with HCL by morphological and immunohistochemical methods presenting to Medical Oncology Ward at Hayatabad Medical Complex, Peshawar since August 2008 were included in the study. Out of 7 patients diagnosed with HCL, 6 were male and 1 was female [MF ratio 61]. Median age at diagnosis was 44 years. Fever, pallor, palpitations and fatigue were the commonest presenting complaints. Spleenomegaly was noted in all patients [100%]. Pancytopenia was noted in all patients at presentation. Five patients were treated with Interferon while 2 were treated with Cladribine. At 18 months of follow-up, one out five patients treated with IFN had relapse while both the patients treated with Cladribine were in complete remission. Our study showed that HCL patients present at a younger age in our region but further studies with larger sample size are required to confirm this. All patients showed a complete response to Interferon and Cladribine with all patients alive at 18 months of follow-up.
Subject(s)
Search on Google
Index: IMEMR (Eastern Mediterranean) Main subject: Leukemia, Hairy Cell / Interferons / Treatment Outcome / Cladribine Limits: Adult / Female / Humans / Male Language: English Journal: J. Postgrad. Med. Inst. Year: 2012

Similar

MEDLINE

...
LILACS

LIS

Search on Google
Index: IMEMR (Eastern Mediterranean) Main subject: Leukemia, Hairy Cell / Interferons / Treatment Outcome / Cladribine Limits: Adult / Female / Humans / Male Language: English Journal: J. Postgrad. Med. Inst. Year: 2012