Association of urinary calcium and phosphate with bone mineral density among postmenopausal women
Biomedica. 2012; 28: 78-81
in English
| IMEMR
| ID: emr-144549
ABSTRACT
Development of peak bone mass and premenopausal bone loss is determined by the menstrual status of a women. Objective of this study was to determine the association of urinary calcium and phosphate with bone loss in post-menopausal women. This study is cross sectional. It was carried out in the Department of Biochemistry, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi. Females [n = 90] were assessed with measurements of Body Mass Index, 24 hour urinary excretion of calcium creatinine ratio, Phosphate creatinine ratio. Bone mineral density of women was evaluated by Dual Energy X-ray Absorptiometrey [DEXA] and its association was analyzed with urinary calcium creatinine ratio and urinary phosphate creatinine ratio. Twenty two [44%] postmenopausal women were found to be osteoporotic while 24 [48%] were osteopenic on the basis of BMD measurements. The mean urinary calcium creatinine ratio and phosphate creatinine ratio was increased in postmenopausal women compared to pre-menopausal women [p < 0.001]. A significant negative correlation was found between BMD [hip] and urinary calcium and phosphate [r = - 0.65, p < 0.05] [r = - 0.58, p < 0.01] respectively in post-menopausal osteoporotic women. Urinary calcium and phosphate creatinine ratio appears to be a valuable markers for assessing bone loss in postmenopausal women
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Osteoporosis
/
Phosphates
/
Absorptiometry, Photon
/
Body Mass Index
/
Bone Density
/
Calcium
/
Cross-Sectional Studies
/
Postmenopause
/
Creatinine
Type of study:
Prevalence study
Limits:
Female
/
Humans
Language:
English
Journal:
Biomedica
Year:
2012
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