Colon adenocarcinoma: cytochemical study of succinic and lactic dehydrogenases under the effect of 5-flurouracil and CCNU antitumour drugs
AJM-Alexandria Journal of Medicine. 1978; 14 (4): 571-575
in English
| IMEMR
| ID: emr-145418
ABSTRACT
The localization and concentration of succinic dehydrogenase [SDH] and lactic dehydrogenase [LDH] in colon adenocarcinoma before and after the application of 5-Fluorouracil [5-Fu] and 1- [2-Chloroethyl] 3-CylohexanylM-Nitrosourea [CCNU] drugs were studied. It was found that there was a marked decrease in the concentration of lactic dehydrogenase [LDH] in the treated cells. On the contrary, the concentration of succinic dehydrogenase [SDH] was found to be increased
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Models, Animal
/
Fluorouracil
/
Histocytochemistry
/
Lomustine
/
Mice
Limits:
Animals
Language:
English
Journal:
Alex. J. Med.
Year:
1978
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