Acute toxicity of some organic solvents in albino rats

Nadia A., Kotb; Fatma El Zhra, Mohamed; Fatma, El Zoairy; H.H., Zayet; Magda A., Dwidar; S.A., El Dessouky

Nadia A., Kotb; Fatma El Zhra, Mohamed; Fatma, El Zoairy; H.H., Zayet; Magda A., Dwidar; S.A., El Dessouky.

Egyptian Journal of Occupational Medicine. 1990; 14 (1): 145-160

in English | IMEMR | ID: emr-145561

ABSTRACT

ABSTRACT

In a trial to verify the cause of Volatile Solvent Abuse [VSA] the acute toxicity of some commonly abused organic solvents were studied in albino rats exposed to the LD 50 of either acetone, toluene or xylene. Blood lipids and histopathological changes were studied in both dead and lwing animals. Electro-Cardiographic tracing was done to the control and survived intoxicated rats. The results obtained suggested profound hyperlipemia, structural damage and myocardial disturbances. Strict legislative measures are recommended

Subject(s)

Male; Animals, Laboratory; Acute Disease; Acetone/toxicity; Toluene/toxicity; Xylenes/toxicity; Electrocardiography; Hyperlipidemias/blood; Cholesterol/blood; Triglycerides/blood; Rats

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Index: IMEMR (Eastern Mediterranean) Main subject: Acetone / Rats / Toluene / Triglycerides / Xylenes / Cholesterol / Acute Disease / Electrocardiography / Hyperlipidemias Limits: Animals Language: English Journal: Egypt. J. Occup. Med. Year: 1990

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