relation between maternal vitamin D levels and their neonates

ABSTRACT

In recent years, despite of the numerous preventive and therapeutic strategies now available, vitamin D deficiency has resurfaced as a global health problem among infants and children. There has been a resurgence of nutritional rickets in children in many developing countries and some developed countries. We evaluate the magnitude of vitamin D deficiency among Kuwaiti mothers and their neonates to provide adequate basis for recommendation to prevent or at least minimize vitamin D deficiency effects. We determined vitamin D levels among mothers and their neonates to detect if their relationship, if any to infantile rickets. One hundred twenty eight full term pregnant mothers and their neonates were selected from medical consultation center in Kuwait. All mothers had normal vaginal delivery. On the day of delivery 2.5ml of maternal blood and 2.5 of cord blood samples were withdrawn .Serum 25-hydroxyvitamin D[25 OHD] was determined in duplicate by radioimmunoassay using lncstar kit. A total 128 mother-neonates pairs were selected from medical consultation center The mean [ +/- SD] age and parity of the mother were 24.7[4,6], 2.48 [1.51] respectively. The mean [ +/- SD] 25OHD levels of mothers their neonates were 17.5 [6.8] ng/ml, 8.1[6,1]ng/ml respectively. Our results demonstrated that vitamin D of the mothers and neonates are highly correlated About 60%of neonates and 45%of their mothers are vitamin D deficient on the day of delivery