Experimental studies on cortical bone xenografts clinical and radiographical assessment

ABSTRACT

An autoclaved cortical bone xenografts of goat cadavers [ACXG] as well as fresh cortical autograft [control FCAG] were successfully used in reconstruction of an experimentally induced segmental femoral defect in canine model. Clinical and radiological assessments were carried out at different periods post-operatively. The obtained results were encouraging and very promising in terms of early return to full limb function at 4-6 weeks post-operatively, cortical union with remodeling were completed at 6 months post-operatively and complete acceptance and incorporation of the graft into the host bone was recorded at 12 months post-operatively. Hence the autoclaved cortical bone xenografts of goat cadavers can offer a worthwhile alternative fo fresh cortical autografts to veterinary orthopedists