[Epidemiology of ESBL enterobacteriaceae in urinary and pulmonary infections in the intensive care units]

ABSTRACT

The nosocomial infections are of a heavy diagnostic and therapeutic burden in intensive care unit [ICU]. The aim of this study is to determine the epidemiology of ESBL-E as an origin infections of urinary and pulmonary infections diagnosed in ICU. This is retrospective study conducted over a period of one year which runs from 1st March 2010 to end February 2011 analyzing the results of cellular and microbiological exams of urine and lung samples; and their corresponding antibiograms. Over three hundred and sixty two positive tests, 167 strains of Enterobacteriaceae were isolated [46%]; fifty six secretory Enterobacteriaceae ESBL producing were isolated with 33.5%. Separately, enterobacteriaceae accounted for 84% of bacteria isolated from urine samples against 31.3% producing about 59%, 44% of all klebsiella are producing ESBL. Multidrug resistance caused by ESBL-E is a universally finding. The results of this study show the gradual increase in their prevalence as important etiological agents of nosocomial infections and therefore their release into the local health environment. It is necessary again to emphasize the importance of hospital hygiene and good rules of antibiotics to limit the spread of MDR bacilli and avoid the therapeutic impasse