Inducible clindamycin resistance among staphylococci isolated from burn patients
LJM-Libyan Journal of Medicine. 2009; 4 (3): 104-106
in English
| IMEMR
| ID: emr-146589
ABSTRACT
Clindamycin has been used successfully to treat pneumonia and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. However, inducible clindamycin resistance has been described as a cause of treatment failure of such infections. A total of 159 staphylococcal isolates from different clinical specimens from burn patients in Tripoli Burn Center were tested for inducible clindamycin resistance by the disk-diffusion induction test. Inducible clindamycin resistance was detected in 66.2% of 65 methicillin-resistant S. aureus isolates and in none of 55 methicillin-sensitive S. aureus, 10 methicillin-resistant coagulase negative staphylococci and 29 methicllin-sensitive coagulase negative staphylococci isolates. In our setting, clindamycin can be used for the treatment of infections due to staphylococci, but we recommend that staphylococci isolates, particularly methicillin-resistant S. aureus, are tested by the D-test before treatment
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Staphylococcal Infections
/
Staphylococcus
/
Staphylococcus aureus
/
Burns
/
Clindamycin
/
Microbial Sensitivity Tests
/
Cross Infection
/
Drug Resistance, Bacterial
Language:
English
Journal:
Libyan J. Med.
Year:
2009
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