Regular intermittent bolus provides similar incidence of maternal fever compared with continuous infusion during epidural labor analgesia
Saudi Medical Journal. 2014; 35 (10): 1237-1242
in English
| IMEMR
| ID: emr-148896
ABSTRACT
To compare the effects of regular intermittent bolus versus continuous infusion for epidural labor analgesia on maternal temperature and serum interleukin-6 [IL-6] level. This randomized trial was performed in Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu Province, China between October 2012 and February 2014. Either regular intermittent bolus [RIB, n=66] or continuous infusion [CI, n=66] was used for epidural labor analgesia. A bolus dose [10 ml of 0.08% ropivacaine + 0.4 microg·ml[-1] sufentanil] was manually administrated once an hour in the RIB group, whereas the same solution was continuously infused at a constant rate of 10 ml·h[-1] in the CI group. Maternal tympanic temperature and serum IL-6 level were measured hourly from baseline to one hour post partum. The incidences of fever [>/= 38°C] were calculated. The incidence of maternal fever was similar between the 2 groups. There was a rising trend in mean temperature over time in both groups, but no statistical difference was detected between the groups at respective time points; maternal serum IL-6 showed similar changes. Compared with continuous infusion, regular intermittent bolus presents with the same incidence of maternal fever for epidural labor analgesia. Interleukin-6 elevation could be involved in mean maternal temperature increase
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Infusions, Intravenous
/
Labor, Obstetric
/
Pregnancy
/
Analgesia, Epidural
/
Fever
Type of study:
Controlled clinical trial
/
Incidence study
Limits:
Female
/
Humans
Language:
English
Journal:
Saudi Med. J.
Year:
2014
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