Frequency of dyslipidaemia in young patients with acute myocardial infarction

ABSTRACT

To study the frequency of dyslipidaemia in young patients aged between 20-40 years, with Acute Myocardial Infarction in our population. Descriptive study. Coronary Care Unit [CCU] of Armed Forces Institute of Cardiology [AFIC]/ National Institute of Heart Diseases [NIHD], Rawalpindi from December 2008 to May 2009. One hundred patients of acute myocardial infarction [AMI] fulfilling the World Health Organization [WHO] diagnostic criteria of AMI, having ages between 20-40 years, were included in the study after full informed consent using non-probability consecutive sampling. Blood samples for serum lipid profile were taken after 12 hours fasting [within 24 hours of presentation], and analyzed in laboratory of AFIC. Individual patients' results were compiled with respect to age, gender, serum total cholesterol, serum triglycerides, serum low density lipoprotein [LDL] cholesterol, serum very low density lipoprotein [VLDL] cholesterol and serum high density lipoprotein [HDL] cholesterol. The data was entered in SPSS [version 11.0] and analyzed. Of the 100 patients with AMI, 47 were found to have dyslipidaemia. Hypertriglyceridaemia was the most common lipid abnormality as it was found in 32 [68.1%] patients; followed by raised serum VLDL, hypercholesterolemia, raised serum LDL and low serum HDL found in 25 [53.2%], 16 [34.0%], 4 [8.5%] and 2 [4.3%] patients respectively. Out of 47 patients with dyslipidaemia, 28 [59.6%] had more than one lipid abnormality. Frequency of dyslipidaemia in young patients with AMI in our population is high.