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Intravenous regional anesthesia [bier's block]; to compare the analgesic effects of combination of 0.5% lidocaine plus ketrolac in intravenous regional anesthesia technique with those of lidocaine 0.5% alone to prevent post operative pain
Professional Medical Journal-Quarterly [The]. 2012; 19 (5): 710-714
in English | IMEMR | ID: emr-151330
ABSTRACT
To compare the analgesic effects of combination of 0.5% Lidocaine plus Ketorolac in intravenous regional anaesthesia technique with those of Lidocaine [0.5%] alone to prevent post operative pain after intravenous regional anaesthesia [Biers block]. Randomized Control Trial. The study was carried out at Department of Anaesthesiology, Intensive Care and pain management, Combined Military hospital, Rawalpindi from July 2008 to February 2009. The study was conducted after complete evaluation of risk / benefit ratio to the patients. On the basis of random number method the patients were divided into two equal groups [group A and group B]. The number of patients in each group was 75. Group A was assigned Lidocaine in a dose of 200mg 40ml of 0.5% solution and group B was assigned injection Ketorolac 30mg added to Lidocaine in a dose of 200mg 40ml of 0.5% solution. The patients were kept in post anaesthesia care unit for two hours and pain intensity was measured by visual analogue scale[VAS] on 15,30 minutes,1hour, 1.5 and at 2 hours after the cuff deflation. The analgesic efficacy recorded on the basis of visual analog scale of two groups, was compared using student's t - test. p value of less than 0.05 was considered statistically significant. In group A 33 males and 42 females were enrolled for the study while in group B there were 38 males and 37 females. The mean age of the patients in group A was 34.31 +/- 6.03 years while in group B was 32.99 +/- 6.08 years. Patients were also classified according to ASA classification in which 87 patients were classified as ASA - I and 63 patients as ASA - II. Group B which received Ketorolac in addition to Lidocaine for Bier's block had low visual analogue scores as compared to group A which received only Lidocaine for Bier's block. P values obtained after the comparison of the mean VAS of two groups at 15 minutes, 30 minutes, 1 hour, 1.5 hours and 2 hours were all less than 0.05 [0.002 for 15 minutes, 0.004 for 30 minutes, 0.001 for 1 hour, 0.004 for 1.5 hours and 0.001 for 2 hours]. Ketorolac improves the postoperative analgesia markedly when used with Lidocaine in intravenous regional anaesthesia
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Index: IMEMR (Eastern Mediterranean) Type of study: Controlled clinical trial Language: English Journal: Professional Med. J.-Q. Year: 2012

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Index: IMEMR (Eastern Mediterranean) Type of study: Controlled clinical trial Language: English Journal: Professional Med. J.-Q. Year: 2012