In-house prepared high fat diet [HFD] can causes an increase in body weight of male albino wistar rats in a short period of 2-3 weeks

ABSTRACT

The current study was designed to evaluate the effects of the in-house prepared high fat diet [HFD] on body weights of rats. Comparative, Experimental Study. The study was conducted at Institute of Basic Medical Sciences [IBMS], Dow University of Health Sciences [DUHS], Ojha Campus, Karachi in a period of 2-3 weeks. The study was conducted on 20 male albino Wistar rats which were randomized into 2 groups each group containing 10 rats. HFD-fed rats were kept on in-house prepared HFD and wate ad libitum throughout the study. While control/ Non-HFD fed rats were kept on standard diet and water. SPSS [version 16.0] was used in the study analysis. The mean difference in body weights of rats was analyzed by using ANOVA.. The results are expressed as mean +/- SD. The results report that there is statistically significant difference [P-value <0.001] between HFD-fed and non HFD-fed groups. HFD-fed group gained significant weight when fed an in-house prepared diet in comparison to non HFD-fed group in 2-3 weeks