Prevalence of IgG and IgM antibodies to human cytomegalovirus among Sudanese renal transplant recipients and haemodialysis patients

ABSTRACT

Human cytomegalovirus [HCMV] is a member of the genus Herpes virus and belongs to the family Herpesviridae. The aim of this research work was to study the prevalence of human cytomegalovirus [HCMV] infection in renal transplant and haemodialysis patients. Blood samples were collected randomly from 52 renal transplant patients and 41 haemodialysis patients. The sera were tested with an enzyme linked immunosorbent assay [ELISA] for HCMV IgG antibodies and additional ELISA test for HCMV IgM antibodies. Renal transplant screening revealed that 98% of patients have IgG for HCMV antibodies and only 6% have IgM antibodies. In haemodialysis patients 95% showed the presence of IgG antibodies to HCMV and non of patient revealed the presence of IgM antibodies