Profile of breast cancer patients

ABSTRACT

To report the profile of patients with breast cancer. Cross sectional study. Department of General Surgery, Dow University of Health Sciences Civil Hospital and Bantva Hospital Karachi, from March 2007 to February 2010. Diagnosis was based on history, clinical examination, Trucut biopsy, FNAC, excision biopsy, frozen sections where applicable. Surgical procedure was tailored according to disease related variables. Induction chemotherapy was given to the patients who present with advance disease, while adjuvant chemotherapy was used in patients with early tumor. Data was collected and recorded; SPSS version 16 was used to analyze the data. This study included 105 patients. Mean age of the patients was 41.9 year. Majority of the patients were with tumor in advance stage. There were 61 [58%] patients in stage III, while 25 were in stage IV [23.8%]. Distant metastases were found in bones [n=16], lungs [n=6] and liver [n=3]. Modified radical mastectomy and axillary clearance was performed in 70 [66.6%] patients. Modified radical mastectomy and axillary sampling was done in 18 [17%] patients. Histopathology confirmed invasive intraductal carcinoma in 99 [94%] cases. Majority of the patients present late with advance disease in younger age group. Modified radical mastectomy was the operative procedure performed in most of the patients