comparison between sublingual misoprostol and intravenous oxytocin for inducing labor in women with term pregnancy

ABSTRACT

In this study efficacy of sub lingual Misoprostol was examined in comparison to Oxytocin [I.V.] for inducing of labor in term pregnancy. Seventy patients were allocated by blocked randomization to Groups A [n=35, sub lingual Misoprostol 25 micro g four hourly to maximum of 5 doses] and B [n=35, continuous Oxytocin infusion]. Delivery active phase and total labor phase were shorter with sublingual Misoprostol in comparison to intravenous Oxytocin [p< 0.001] and the rate of cesarean section was lower in Misoprostol group [p<0.04] but delivery latent phase, meconium staining, uterine hypertonisity and apgar score [1 and 5 minute] were similar in two groups. Sublingual Misoprostol is better than intravenous Oxytocin for induction of labor at term