Frequency of proteinuria in patients with older-onset diabetes mellitus attending civil hospital Karachi

ABSTRACT

To determine the frequency of proteinuria in patients with adult-onset diabetes mellitus. Descriptive study. This study was conducted at Medical Wards of Civil Hospital Karachi from 1[st] November 2010 to 30[th] April 2011. In this study 100 patients of adult onset diabetes mellitus were enrolled who were admitted in medical department at Civil Hospital Karachi. The duration of the study was 6 months. Diagnosed all patients with type 2 diabetes mellitus and > 40 years of age were included except for patients with urinary tract infection, haematuria, acute febrile illness, congestive cardiac failure, uncontrolled hypertension. A mid-stream urine sample was collected for the determination of UAE; Macroalbuminuria was tested first if it was found negative then urine was tested for Microalbuminuria. Out of 100 patients 55% patients had normal Albuminuria [<20 mg/liter] while 45% patients had evidence of increased proteinuria [>20 mg/liter]. Out of 45 proteinuric patients, 28[62.2%] patients had evidence of Microalbuminuria [cutoff; 20-200 mg/liter] and 17[37.8%] patients had Macroalbuminuria [cutoff; >200 mg/liter]. The concluded that the frequency of microalbuminuria is higher than macroalbuminuria in type 2 diabetic subjects: