Phytochemical and biological study of vangueria edulis cultivated in Egypt
Bulletin of Pharmaceutical Sciences-Assiut University. 2012; 35 (Part 1): 67-81
in English, Arabic
| IMEMR
| ID: emr-154257
ABSTRACT
Fractionation and purification of the alcoholic extract of the leaves and stem -bark of Vangueria edulis cultivated in Egypt afforded thirteen compounds identified as p-sitosterol acetate [1], stigmasterol [2], palmitic acid [3], scopoletin [4], p-coumaric acid [5], protocatechuic acid [6], esculetin [7], ethyl I-O-glucosyi-4-O-[E] caffeoyl quinate [8], kaempferol 3-O-rhamnoside, 7-O-rutinoside [9], p-sitosterol [10], ceryl alcohol [11], vanillic acid [12] and p-sitosterol-3-Q-beta-D-glucopyranoside [13]. Identification of these compounds has been established by physical, chemical and spectral data as well as comparison with authentic samples. Compounds 8 and 9 are firstly reported from a natural source while the rest of the compounds have been isolated for the first time from the genus Vangueria. The LD[50] antibacterial antifungal anti-inflammatory, antipyretic and the effect on CNS were studied
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Rats
/
Scopoletin
/
Umbelliferones
/
Mice
/
Anti-Inflammatory Agents
/
Anti-Bacterial Agents
/
Antifungal Agents
Limits:
Animals
Language:
Arabic
/
English
Journal:
Bull. Pharm. Sci.-Assiut Univ.
Year:
2012
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