IJPR-Iranian Journal of Pharmaceutical Research. 2015; 14 (1): 131-140
in English
| IMEMR
| ID: emr-154874
ABSTRACT
Diabetes mellitus is the most common endocrine disorder, causes many complications such as micro- and macro-vascular diseases. Anti-diabetic, hypolipidemic and anti-oxidative properties of ginger have been noticed in several researches. The present study was conducted to investigate the effects of ginger on fasting blood sugar, Hemoglobin A1c, apolipoprotein B, apolipoprotein A-I, and malondialdehyde in type 2 diabetic patients. In a randomized, double-blind, placebo-controlled, clinical trial, a total of 41 type 2 diabetic patients randomly were assigned to ginger or placebo groups [22 in ginger group and 19 in control group], received 2 g/day of ginger powder supplement or lactose as placebo for 12 weeks. The serum concentrations of fasting blood sugar, Hemoglobin A1c, apolipoprotein B, apolipoprotein A-I and malondialdehyde were analyzed before and after the intervention. Ginger supplementation significantly reduced the levels of fasting blood sugar, hemoglobin A1c, apolipoprotein B, apolipoprotein B/apolipoprotein A-I and malondialdehyde in ginger group in comparison to baseline, as well as control group, while it increased the level of apolipoprotein A-I [p<0.05]. It seems that oral administration of ginger powder supplement can improves fasting blood sugar, hemoglobin A1c, apolipoprotein B, apolipoprotein A-I, apolipoprotein B/apolipoprotein A-I and malondialdehyde in type 2 diabetic patients. So it may have a role in alleviating the risk of some chronic complications of diabetes
Search on Google
Index:
IMEMR (Eastern Mediterranean)
Main subject:
Apolipoproteins B
/
Blood Glucose
/
Glycated Hemoglobin
/
Double-Blind Method
/
Fasting
/
Apolipoprotein A-I
/
Diabetes Mellitus, Type 2
/
Malondialdehyde
Type of study:
Controlled clinical trial
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Iran. J. Pharm. Res.
Year:
2015
Similar
MEDLINE
...
LILACS
LIS