Cytogenetics of fetal wastage in Bahrain

ABSTRACT

A consecutive series of fifty couples with a history of fetal wastage was studied cytogenetically with current banding techniques. Fetal wastage was defined as occurring in couples who had more than two early abortions, still-birth[s] of live-birth[s] or both of infants with multiple congenital anomalies. One couple was found to be balanced reciprocal translocation carriers. One woman was found to have Robertsonian Translocation, another woman was found to be mosaic [46, XX, 47, XXX]; and one husband was found to have pericentric inversion of Y chromosome. We find that parental chromosome abnormalities account for fetal wastage in 8% of couples having such a history