[Comparison of blood loss in femoral shaft surgeries between tranexamic acid and controlled hypotension]

ABSTRACT

Blood loss reducing approaches improve surgery outcomes through producing an appropriate operation field and reducing transfusion need. In this study two blood loss reducing techniques were compared. In a randomized clinical trial study 60 patients candidate for elective femoral shaft operation were devided in two groups. The first group went under induced hypotensionand the second group received tranexamic acid. Anesthesia technique and surgeon were the same in both groups. Bleeding amountwas measured based on site operation site and reservoir observing, pads counting. Traputic interventions such as crystalloids or colloids and blood transfusion were done as needed. Results were evaluated by Mann-witney U test. Dry field and surgeons satisfaction was good in 23 patinets of the hypotention group [76%] and was moderate in the rest of the group. In the tranexamic group the results were good in 21 patients [70%]. There was no significant difference in reducing blood loss between the groups. Both of the studied techniques can reduce bleeding and improve operation field and surgeon satisfaction, meanwhile there was no significant difference in two approaches