problem of typhoid fever diagnosis and management: a review article

ABSTRACT

Enteric or typhoid fever is a global health problem affecting millions of people annually and endemic in many countries. The classical presentation includes fever, malase, diffuse abdominal pain and constipation. Untreated typhoid fever may progress to delirium, intestinal hemorrhage, bowel perforation and even death within one month of onset. There are many problems regarding diagnosis and management. In this study a reprehensive number of practicing clinicians, pathologists and laboratory technicians were asked to complete a specially designed questionnaire for each group. The questions covered areas of clinical diagnosis, laboratory diagnosis and drug management. Results showed a number of misconceptions especially regarding laboratory diagnosis and drug treatment. Standard internationally accepted methods of laboratory diagnosis and top recommended drugs [including dose and duration] were presented in the review. Finally, we hope this review will contribute in solving the problem of diagnosis and management of enteric fever and we recommend distributing guidelines for diagnosis and management