Study of extracranial blood flow and haemorhelogic factors in patients with cerebral vascular disease

ABSTRACT

This study was carried out to evaluate the role of extra- cranial blood vessels and hemorheological parameters in the pathogenesis of cerebral ischemia. So, a 50 patients with cerebrovascular disease and 20 healthy controls were subjected to assessment of vascular changes in the carotid arteries by ultrasonic Doppler flowmeter and some blood factors such as blood viscosity, red cell deformability and plasma fibrinogen. Blood vessel studies revealed vascular lesions in the carotid arteries in the form of atherosclerotic lesions with and without stenosis, while blood factors showed a significant increased level in patients with cerebral ischemia. There was a positive correlation between the vascular changes and the hemorheologic variables in patients suffering from cerebral ischemia. Also, extracranial blood vessels [Carotids] were demonstrated to have a role in the pathogenesis of cerebral ischemia