Acute graft-versus-host disease in thalassaemic marrow transplantation with low-dose antithymocyte globulin
EMHJ-Eastern Mediterranean Health Journal. 1999; 5 (3): 465-469
in English
| IMEMR
| ID: emr-156636
ABSTRACT
Our unit performed transplantations on 21 classes II and III thalassaemic patients [class II patients had either hepatomegaly or portal fibrosis and class III patients had both]. We used busulfan [15 mg/kg] and cyclophosphamide [200 mg/kg]. Graft-versus-host disease [GVHD] prophylaxis was cyclosporin, prednisolone and low-dose antithymocyte globulin. Our patient data showed a low incidence of acute GVHD following transplantation. We offer this regimen as an acceptable therapy for thalassaemic patients undergoing allogeneic marrow transplantation as a safe clinical procedure, irrespective of the class of patient
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Thalassemia
/
Transplantation, Homologous
/
Prednisolone
/
Acute Disease
/
Bone Marrow Transplantation
/
Cyclosporins
/
Graft vs Host Disease
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
East Mediterr Health J.
Year:
1999
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