Serum endostatin and vascular endothelial growth factor levels in patients with pre-eclampsia
EMHJ-Eastern Mediterranean Health Journal. 2006; 12 (1-2): 178-187
in English
| IMEMR
| ID: emr-156867
ABSTRACT
We evaluated the prognostic value of serum endostatin and vascular endothelial growth factor [VEGF] for diagnosis of pre-eclampsia. We determined VEGF and endostatin levels in the sera of 20 healthy, non-pregnant women and 64 pregnant women 20 healthy, 20 with mild pre-eclampsia and 24 with severe pre-eclampsia. Serum levels of these factors in non-pregnant women were similar to those in healthy pregnant women. However, serum levels were significantly higher with mild or severe pre-eclampsia compared with normal pregnancies and significantly higher with severe rather than with mild pre-eclampsia. Elevated levels significantly increased risk more than severity of pre-eclampsia. VEGF and endostatin could be used to differentiate between pre-eclamptic and normal pregnancies and to discriminate mild pre-eclampsia from severe pre-eclampsia
Search on Google
Index:
IMEMR (Eastern Mediterranean)
Main subject:
Pre-Eclampsia
/
Pregnancy
/
Endothelial Growth Factors
/
Vascular Endothelial Growth Factor A
Limits:
Female
/
Humans
Language:
English
Journal:
East Mediterr Health J.
Year:
2006
Similar
MEDLINE
...
LILACS
LIS