Neuroleptic-induced tardive dyskinesia among Arab psychotic patients

ABSTRACT

We carried out a retrospective descriptive study to determine prevalence and risk factors for tardive dyskinesia [TD] among psychotic patients treated with conventional neuroleptics in 4 centres in Saudi Arabia. Records of patients who had been taking neuroleptic for patients were included in the final analysis. Only 51 had TD; another 59 [6.8%] patients had drug-induced Parkinson disease. Duration of treatment [P < 0.001], higher doses of neuroleptics [P < 0.01] and age over 40 years [P < 0.01] were associated with TD. A statistically significant difference in prevalence was found between Arabs [23.5%] and Afro-Arabs [45.5%] [P < 0.01]. Overall prevalence of TD among psychotic patients was 5.9%