use of T-lymphocytes subsets as a non specific test for detection of viral infection in blood transfusion service

ABSTRACT

Many viral diseases can be transmitted through blood transfusion. It is not easy to diagnose each of these diseases separately, therefore, this study aimed to adopt a non specific test on hope that it would cover this extending array of infectious diseases [CD4/CD8 ratio]. This study proved that this ratio was significantly decreased in donors to recipients who experienced CMV infection therefore this study presents an evidence that CD4/CD8 ratio has a potential role to play in blood banks to exclude donors who are carriers to those viruses