Distinguishing between primary infection and reinfection with rubella vaccine virus by IgG avidity assay in pregnant women
EMHJ-Eastern Mediterranean Health Journal. 2009; 15 (1): 94-103
in English
| IMEMR
| ID: emr-157302
ABSTRACT
During the mass measles/rubella vaccination campaign in 2003 in Iran, many pregnant women were vaccinated mistakenly or became pregnant within 1 month of vaccination. To distinguish pregnant women who were affected by rubella vaccine as primary infection from those who had rubella reinfection from the vaccine, serum samples were collected 1-3 months after the campaign from 812 pregnant women. IgG avidity assay showed that 0.3% of the women had no rubella-specific IgG response; 14.4% had low-avidity anti-rubella IgG and were therefore not immune to rubella before vaccination; 85.3% had high-avidity antirubella IgG and were regarded as cases of reinfection
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Rubella
/
Immunoglobulin G
/
Pregnancy
/
Antibody Affinity
Limits:
Female
/
Humans
Language:
English
Journal:
East Mediterr Health J.
Year:
2009
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