Your browser doesn't support javascript.
loading
Antioxidant status and lipid peroxidation activity in evaluating hepatocellular damage in children
EMHJ-Eastern Mediterranean Health Journal. 2009; 15 (4): 842-852
in English | IMEMR | ID: emr-157386
ABSTRACT
Serum levels of glutathione reductase [GR], glutathione S-transferase-alpha [GST-alpha] and malondialdehyde [MDA] were determined to evaluate their use in diagnosing hepatocellular damage in 75 children with liver disease. Except for level of GR in patients with HBV, GR, GST-alpha and MDA were raised significantly in patients compared with controls. At 100% specificity, the sensitivity of the 3 markers for detecting hepatitis B virus, hepatitis C virus and schistosomiasis infection respectively were 16.7%, 100.0% and 17.7% for GR; 33.3%, 62.1% and 38.2% for GST-alpha; and 25.0%, 10.3% and 29.4% for MDA. GR was more sensitive in hepatitis C infection, while MDA reflected changes in liver ultrasound and GST-alpha was the best indicator for histopathological changes
Subject(s)
Search on Google
Index: IMEMR (Eastern Mediterranean) Main subject: Schistosomiasis / Biopsy / Sensitivity and Specificity / Hepatitis C / Oxidative Stress / Glutathione Reductase / Glutathione Transferase / Hepatitis B / Liver Diseases / Liver Function Tests Limits: Female / Humans / Male Language: English Journal: East Mediterr Health J. Year: 2009

Similar

MEDLINE

...
LILACS

LIS

Search on Google
Index: IMEMR (Eastern Mediterranean) Main subject: Schistosomiasis / Biopsy / Sensitivity and Specificity / Hepatitis C / Oxidative Stress / Glutathione Reductase / Glutathione Transferase / Hepatitis B / Liver Diseases / Liver Function Tests Limits: Female / Humans / Male Language: English Journal: East Mediterr Health J. Year: 2009