[Effect of resistance exercise on protein content and mRNA expression of NT 4/5 in rat slow and fast muscles]
Journal of Gorgan University of Medical Sciences. 2014; 16 (1): 35-41
in Persian
| IMEMR
| ID: emr-157571
ABSTRACT
Trophic factor family plays a key role for neuromuscular system healthy. This study was carried out to determine the effect of one session of resistance exercise on protein content and mRNA expression of NT4/5 in rat slow and fast muscles. In this experimental study, sixteen adult male rats randomly were allocated into resistance exercise [T] and control groups. The resistance training protocol consisted of climbing a 1-meter-long ladder, with a weight attached to a tail sleeve. Quantitative Real time RT-PCR for NT-4/5 expression and ELISA Kit for protein assay were used. Resistance training significantly decreased mRNA expression and increased protein of NT4/5 in soleus muscle [P<0.05]. Significant alteration was not detected in flexor hallucis longus muscle. One session of resistance training can alter protein and mRNA of NT-4/5 in skeletal muscle and this alteration was dependent on muscle type
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Physical Conditioning, Animal
/
Rats
/
RNA, Messenger
/
Enzyme-Linked Immunosorbent Assay
/
Random Allocation
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Receptors, Nerve Growth Factor
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Muscle, Skeletal
/
Reverse Transcriptase Polymerase Chain Reaction
Limits:
Animals
Language:
Persian
Journal:
J. Gorgan Univ. Med. Sci.
Year:
2014
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