Association of body mass index and dietary habits with ovarian and uterine morphology with sub fertile polycystic ovarian syndrome

ABSTRACT

To correlate ovarian and uterine morphology in sub fertile patients having polycystic ovarian syndrome with their body mass index [BMI] and eating habits One hundred subjects were included in this cross sectional study having ages between 20-40 years with history of subfertility for the past two years. BMI [kg/m2] was measured according to WHO protocol. Ovarian volume, follicle count and size, uterine area, endometrial thickness were measuredsonographically and noted. Dietary habits were recorded by a structured questionnaire from all participants According to BMI two groups of 50 subjects each were formed; group I= 25.6 +/- 4.7 kg/m2 and group II= 28.6 +/- 5.7 kg/m2. The follicular count was 14.41 +/- 2.18 and 12.75 +/- 2.80; the follicular size [in mm] was 8.23 +/- 0.41and 3.29 +/- 0.25 [p-value 0.023 and 0.001]. The uterine area [in cm2] and endometrial thickness [in cm] was 86.9 +/- 25.7 and 117.2 +/- 29 [p-value 0.001 and0.05]. The ovarian volume [OV] estimated by trans-abdominal scan [TAS] was10.87 +/- 2.49 cm3 and 14.33 +/- 3.17 cm3 [p-value=0.022]. The trans-vaginal scan[TVS] showed OV; 11.44 +/- 2.36 cm3 and 14.79 +/- 2.19 cm3 [p-value=0.034]. A weak positive correlation of BMI with OV [TVS] was observed [r=0.05]. The ovarian volume in those women who consumed fast food frequently was significantly raised as compared to those who rarely ate fast food; the difference was 14.57 +/- 3.75 vs. 9.62 +/- 2.43 [p value 0.00]. With increasing body mass index the ovarian volume, uterine area and endometrial thickness increases. However the follicular count and follicular size is reduced with higher BMI