Suitability of soluble transferrin receptor for the clinical diagnosis of different types of anaemia in children
EMHJ-Eastern Mediterranean Health Journal. 2002; 8 (2-3): 298-307
in English
| IMEMR
| ID: emr-158064
ABSTRACT
We evaluated the ability of serum transferrin receptor [sTFR] to identify different types of anaemia in children. Thus 150 Egyptian children suffering from anaemia [iron deficiency anaemia, anaemia of chronic disease and beta-thalassaemia] were enrolled, together with 50 controls. There was a significant increase in the mean levels of sTFR in the groups with iron deficiency anaemia and thalassaemia, and a significant decrease in mean sTFR levels in the group with anaemia of chronic disease. Serum ferritin levels were significantly higher in all patient groups except the group with iron deficiency anaemia. There were also significant correlations between the sTFR and sTFR/log ferritin ratio [sTFR-F index] and different indices of iron status and of erythropoiesis. The sTFR-F index could be used as a diagnostic or screening tool for iron deficiency anaemia, anaemia of chronic disease and thalassaemia
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Thalassemia
/
Child Nutrition Disorders
/
Case-Control Studies
/
Nutrition Assessment
/
Child
/
Nutrition Surveys
/
Immunoenzyme Techniques
/
Anemia, Iron-Deficiency
/
Ferritins
Type of study:
Controlled clinical trial
Limits:
Adolescent
/
Child
/
Female
/
Humans
/
Infant
/
Male
Language:
English
Journal:
East Mediterr Health J.
Year:
2002
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