Visceral leishmaniasis in the Syrian Arab Republic: early detection using rK39
EMHJ-Eastern Mediterranean Health Journal. 2003; 9 (4): 856-862
in English
| IMEMR
| ID: emr-158222
ABSTRACT
Leishmaniasis causes significant morbidity and mortality in areas where it is endemic. A seroprevalence survey was conducted in 2 endemic villages in Daraa, Syrian Arab Republic, where 80 out of 345 children [23.2%] tested positive for visceral leishmaniasis [VL] using rK39 dipstick test. Only 10 cases were symptomatic [12.5%], and 27.5% were positive by ELISA test. All the sera [N = 138] obtained from the control village were negative. Of the rK39 initially positive cases, 52 had seroconverted to negative 9 months later, 55 remained ELISA negative, and none developed the full-blown disease. Being faster and less expensive than other diagnostic tests, rK39 is a rapid, sensitive and specific diagnostic tool for symptomatic cases of VL in remote areas with poor accessibility to health services
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Reagent Strips
/
Leishmania donovani
/
Enzyme-Linked Immunosorbent Assay
/
Protozoan Proteins
/
Mass Screening
/
Cross-Sectional Studies
/
Health Surveys
/
Sensitivity and Specificity
/
Health Services Accessibility
/
Medically Underserved Area
Type of study:
Prevalence study
/
Screening study
Limits:
Animals
/
Humans
Language:
English
Journal:
East Mediterr Health J.
Year:
2003
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