Quinine therapy in severe Plasmodium falciparum malaria during pregnancy in Sudan
EMHJ-Eastern Mediterranean Health Journal. 2004; 10 (1-2): 159-166
in English
| IMEMR
| ID: emr-158272
ABSTRACT
A prospective study was carried out in an area of unstable malaria transmission in central Sudan to determine the efficacy and toxicity of quinine in pregnancy. Thirty-three pregnant women with severe Plasmodium falciparum malaria at mean 28.8 weeks gestational age were treated with quinine for 7 days. The mean body temperature on presentation for 3 patients who delivered prematurely was significantly higher than for those who delivered at term [39.2 +/- 0.7 degrees C versus 38.7 +/- 1.3 degrees C]. There were no significant difference between the 2 groups in other clinical or biochemical parameters. There were no clinically detectable congenital malformations and no auditory, visual or other neurological deficits in the babies at birth or 6 months later. Quinine may be safe in the treatment of severe falciparum malaria during pregnancy
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Body Temperature
/
Infusions, Intravenous
/
Drug Administration Schedule
/
Pregnancy Outcome
/
Administration, Oral
/
Gestational Age
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
East Mediterr Health J.
Year:
2004
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