Antiphospholipid syndrome and retinal vein occlusion in adults
EMHJ-Eastern Mediterranean Health Journal. 2004; 10 (4-5): 627-632
in English
| IMEMR
| ID: emr-158330
ABSTRACT
Antiphospholipid antibodies may play and important role in the pathogenesis of retinal vascular occlusions; investigated the prevalence among 33 patients with retinal vein and artery occlusions and 80 controls. Prevalence was 33% and 5% respectively. Ophthalmic examination and fluorescein angiography showed that occlusions were due to ischaemic events. The 11 patients were diagnosed with antiphospholipid syndrome 9 patients were treated successfully with laser photocoagulation and anticoagulant and anti-aggregant therapy. Two patients with antiphospholipid antibodies associated with resistance to activated protein C had unfavourable outcomes. Our results suggest a correlation between antiphospholipid syndrome and retinal vein occlusions; we recommend a systematic search for antiphospholipid antibodies in occlusions of unexplained origin and laser photocoagulation treatment and long-term oral anticoagulant and anti-aggregant therapy
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Retinal Vein Occlusion
/
Fluorescein Angiography
/
Case-Control Studies
/
Chi-Square Distribution
/
Administration, Oral
/
Laser Coagulation
/
Antibodies, Antiphospholipid
/
Anticoagulants
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
East Mediterr Health J.
Year:
2004
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