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Hepatitis C virus infection among paediatric patients attending University of Assiut Hospital, Egypt
EMHJ-Eastern Mediterranean Health Journal. 2010; 16 (4): 356-361
in English | IMEMR | ID: emr-158427
ABSTRACT
Few studies have evaluated the epidemiology and risk factors of hepatitis C virus [HCV] infection in children in Egypt. This study of 465 children attending Assiut University Hospital measured the rates of anti-HCV positivity by 3rd-generation ELISA test and of HCV-RNA positivity by PCR, with analysis of some relevant risk factors. The rate of HCV-RNA positivity among ELISA-positive cases [n = 121] was 72.2% overall 100% in the subgroup with hepatitis, 70.8% in those with a history of multiple transfusions and 58.3% in those without hepatitis or multiple transfusions. History of blood transfusions, frequent injections, hospitalization or surgical procedures were significant risk factors for anti-HCV positivity by ELISA
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Index: IMEMR (Eastern Mediterranean) Main subject: Blood Transfusion / Enzyme-Linked Immunosorbent Assay / Surveys and Questionnaires / Risk Factors / Infection Control / Hepatitis C / Hepacivirus / Hospitals, University Type of study: Controlled clinical trial Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Language: English Journal: East Mediterr Health J. Year: 2010

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Index: IMEMR (Eastern Mediterranean) Main subject: Blood Transfusion / Enzyme-Linked Immunosorbent Assay / Surveys and Questionnaires / Risk Factors / Infection Control / Hepatitis C / Hepacivirus / Hospitals, University Type of study: Controlled clinical trial Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Language: English Journal: East Mediterr Health J. Year: 2010