What do we need to eradicate rubella in the Islamic Republic of Iran?
EMHJ-Eastern Mediterranean Health Journal. 2013; 19 (9): 807-811
in English
| IMEMR
| ID: emr-159195
ABSTRACT
To evaluate the need for congenital rubella syndrome prevention in our national health programme we aimed to determine the rate of anti-rubella positivity in umbilical cord blood samples 8 years after measlesrubella mass vaccination in the Islamic Republic of Iran. In a cross-sectional study we tested umbilical cord blood samples for anti-rubella IgG and IgM by ELISA in 154 deliveries at a university hospital in Tehran. Overall 72.7% of umbilical cord blood samples were positive for anti-rubella IgG and 27.3% were negative. All of the samples were negative for anti-rubella IgM. In the samples with a history of mothers' rubella vaccination, only 87.5% were positive for anti-rubella IgG. The results suggest the need for another mass vaccination for rubella in women of child-bearing age and continuation of routine vaccination of infants, plus consideration of obligatory anti-rubella IgG testing before pregnancy in women who were not vaccinated and vaccination of women before marriage.
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Immunoglobulin G
/
Immunoglobulin M
/
Enzyme-Linked Immunosorbent Assay
/
Cross-Sectional Studies
/
Vaccination
/
Fetal Blood
/
Disease Eradication
Type of study:
Prevalence study
Limits:
Female
/
Humans
Language:
English
Journal:
East Mediterr Health J.
Year:
2013
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