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What do we need to eradicate rubella in the Islamic Republic of Iran?
EMHJ-Eastern Mediterranean Health Journal. 2013; 19 (9): 807-811
in English | IMEMR | ID: emr-159195
ABSTRACT
To evaluate the need for congenital rubella syndrome prevention in our national health programme we aimed to determine the rate of anti-rubella positivity in umbilical cord blood samples 8 years after measles–rubella mass vaccination in the Islamic Republic of Iran. In a cross-sectional study we tested umbilical cord blood samples for anti-rubella IgG and IgM by ELISA in 154 deliveries at a university hospital in Tehran. Overall 72.7% of umbilical cord blood samples were positive for anti-rubella IgG and 27.3% were negative. All of the samples were negative for anti-rubella IgM. In the samples with a history of mothers' rubella vaccination, only 87.5% were positive for anti-rubella IgG. The results suggest the need for another mass vaccination for rubella in women of child-bearing age and continuation of routine vaccination of infants, plus consideration of obligatory anti-rubella IgG testing before pregnancy in women who were not vaccinated and vaccination of women before marriage.
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Index: IMEMR (Eastern Mediterranean) Main subject: Immunoglobulin G / Immunoglobulin M / Enzyme-Linked Immunosorbent Assay / Cross-Sectional Studies / Vaccination / Fetal Blood / Disease Eradication Type of study: Prevalence study Limits: Female / Humans Language: English Journal: East Mediterr Health J. Year: 2013

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Index: IMEMR (Eastern Mediterranean) Main subject: Immunoglobulin G / Immunoglobulin M / Enzyme-Linked Immunosorbent Assay / Cross-Sectional Studies / Vaccination / Fetal Blood / Disease Eradication Type of study: Prevalence study Limits: Female / Humans Language: English Journal: East Mediterr Health J. Year: 2013