Novel 8-methyl-8-azabicyclo [321] oct-3-yl coumarinyloxy] acetates as potential anticholinergic agents
Egyptian Journal of Pharmaceutical Sciences. 1990; 31 (1-4): 1-11
in English
| IMEMR
| ID: emr-16000
ABSTRACT
The synthesis of esters of 31-hydroxy-8-methyl-8-azabicyclo [3.2.1] octane with various [coumarinyloxy] acetic acids is described. Some quaternary salts were also prepared from the corresponding tertiary esters and dimethyl sulphate. Six of the new esters evaluated in terms of anticholinergic activity showed significant antispasmodic action without mydriatic effect
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Index:
IMEMR (Eastern Mediterranean)
Language:
English
Journal:
Egypt. J. Pharm. Sci.
Year:
1990
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