Postoperative outcomes in patients with chronic renal failure undergoing coronary artery bypass grafting in madani heart center: 2000-2010

ABSTRACT

Renal failure predisposes patients to adverse outcome after coronary artery bypass grafting [CABG] Renal dysfunction is a predictor of increased morbidity and mortality after CABG, whether it is dialysis-dependent or not. In a retrospective study from April 2000 to December 2010, seventy-six patients [60 male and 16 female with the mean age of 58.57+7.93 years] with different categories of chronic renal failure undergoing CABG in Shahid Madani Hospital, were studied. The cardiac disease leading to the operation was coronary artery disease [CAD] in all patients. Patients demographic, surgical and laboratory data were gathered from hospital records. Data were then analyzed. Mean hospital stay was 10.16+7.16 days. The preoperative mortality rate was 10.5% [15% in non dialysis and 5.6% in dialysis dependant patients with no significant difference]. Morbidity rate was 28.9% [respectively 30% and 27.8% in dialysis and non dialysis patients with no significant difference] including in-hospital myocardial infarction [MI] [10.5%], in-hospital stroke [2.6%], in-hospital bleeding [21.1%] and in-hospital infection, pneumonia, [5.3%]. Mean creatinine and blood urea nitrogen [BUN] levels were significantly increased after surgery [p0.001]. Postoperative hemodialysis rate was 33.3%. Chronic renal failure whether dialysis-dependant or not increases in-hospital mortality and morbidity in patients undergoing CABG. For CRF patients not on dialysis with a creatinine 2.5 gm/dL, there is a strong likelihood of postoperative dialysis