Significance of platelet count and D-dimers level in carcinoma prostate

ABSTRACT

Analysis and recognition of coagulopathies in patients with carcinoma of prostate by carrying out platelet count and D-dimers level. Case-control study. This study was conducted at ISRA Hospital, Hyderabad, Liaquat University of Medical and Health Sciences Hospital Hyderabad and NIMRA Jamshoro for a period of six months from from June 2011 to November 2011. Cases were patients with prostatic carcinoma who were diagnosed on biopsy examination. Controls were normal healthy randomly selected age matched adult males from Hyderabad without prostatic carcinoma. A total of one hundred subjects were included in the study. In Group I [Cases], the mean platelet count was 197.52 x 103 and in Group II [Controls], the mean platelet count was 286.06 x 103. In Group I [Cases], the mean D-dimers level was 0.692 mg/L and in Group II [Controls], the mean D-dimers level was 0.146 mg/L. Coagulopathies are frequently associated with prostate cancer and should be known to urologists and oncologists because they may compromise short-term prognosis and influence therapeutic strategies. Our results suggest that platelet count and D-dimer levels are altered in patients with prostate cancer