Effect of aerobic and resistance training; the skeletal muscle mitochondrial function in the spirit study cohort

ABSTRACT

The aim of this investigation was to examine the effect of aerobic and resistance training on the skeletal muscle mitochondrial function. Wellington Hospital New Zealand, Massey University, Wellington Campus New Zealand. Sep 2008- Sep 2011. There was a very large effect [6.7 +/- 1.2] in the AER group for BHAD activity whereas in the PRT group a large effect [2.7 +/- 1.2] for BHAD activity was observed. There was an increase in CS activity in both groups [PRT; p = 0.007, AER; p=0.03] however, the activity increase was more in the PRT group [effect size = 1.8 +/- 1.3]. COX activity was raised in both groups as well though the effect size in the PRT group was 2.3 +/- 1.2 meaning a very large change with PRT exercise compared to a moderate effect [1.0 +/- 1.2] with AER exercise. Overall these findings suggest that both PRT and AER exercise can be effective therapeutic modalities for the induction of changes at the cellular level in muscle of people with T2DM