Effect of miconazole oral gel in the treatment of dentureinduced stomatitis

ABSTRACT

The aim of this study is to assess the efficacy of Miconazole Oral Gel in the treatment of denture induced stomatitis and to compare it to the use of corrective and hygienic measures only. Method: Forty two prosthodontic patients, wearing removable prosthesis and presenting with denture stomatitis, were divided equally and randomly into two groups. Group A received Miconazole Oral Gel in addition to oral hygiene instructions, denture cleansers, and correction of denture faults, and group B received the same treatment with the exception of Miconazole Oral Gel. Clinical and mycological examinations using Sabourauds Dextrose Agar Media were done for each patient in both groups, and were repeated for each in the follow up visits. Data were collected, tabulated, and statistical analysis was done to find inter- and intra-group differences. Results revealed that candidal count and the erythema of the underlying mucosa were significantly reduced in both groups at follow-up visits compared with the pretreatment condition, but the reduction was significantly more in the group that received Miconazole Oral Gel. Oral hygiene instructions play an important role in reducing severity of the condition, but they should be used in combination with Miconazole Oral Gel to gain the best results: