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[Role of Re-resection of non-muscle invasive bladder cancer T1 in treatment and prognosis]
JABHS-Journal of the Arab Board of Health Specializations. 2014; 15 (4): 13-18
in Arabic | IMEMR | ID: emr-162443
ABSTRACT
Bladder cancer is the most common malignancy of the urinary tract. Approximately 75% of patients present with a non-muscle-invasive bladder tumors. It is recommended to perform a second resection [Re-TURBT] of T1, and high grade tumors after 2-6 weeks from the initial TURBT. This retrospective study was performed to determine the role of re-resection [Re-TURBT] of non-muscle invasive T1 bladder cancer after 4-6 weeks from the first resection. From January 2011 to December 2013, we retrospectively evaluated 108 patients with primary T1 TCC [transitional cell carcinoma] bladder cancer. Re-TURBT was performed in 70 patients [group A] after 4-6 weeks from initial TURBT, 38 underwent regular follow up without re-resection [group B]. A cystoscopy was performed every 3 months for 1 year in all patients. Both groups [A+B] received 6 doses course of BCG as an adjuvant therapy. Residual disease at the second TURBT was detected in 41 patient [58.5%].Understaging in initial TURBT was found in 11 patients [15.7%], 6 [8.5%] of them were T2 and underwent cystectomy. Recurrence happened in 21 [32.8%] patients of group A [64 patients] and in 25 patients [65.7%] of group B. Progression to muscle invasive tumors in 4 [6%] in group A, in 6 [15%] in group B. Recurrence was reduced from 65.7% in group B to 32.8% in group A [p=0.001] and progression reduced from 15% to 6%, [p=0.11]. Re-TURBT has an important role in correcting understaging in initial TURBT, and it reduces recurrence and progression in patients with T1 bladder tumors. We recommend re-TURBT in T1 bladder tumor patients
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Index: IMEMR (Eastern Mediterranean) Language: Arabic Journal: J. Arab Board Health Special. Year: 2014

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Index: IMEMR (Eastern Mediterranean) Language: Arabic Journal: J. Arab Board Health Special. Year: 2014