Insulin resistance and polycystic ovary syndrome

ABSTRACT

Polycystic ovarian syndrome is a heterogeneous disorder, characterized by cystic ovarian morphology, androgen excess and irregular periods that occurs during or shortly after the onset of puberty. Insulin resistance and consequent hyperinsulinemia during this disorder promotes an ongoing state of androgen excess. This syndrome can be adequately managed by changes in lifestyle, controlled intake of diet, regular exercise along with proper medication. Reduction in insulin resistance causes improved action of androgen on target tissues that offers the possibility of improvement in the physical stigmata of androgen excess leading to correction of the reproductive dysfunction and prevention of metabolic derangements