Single versus multimodel analgesia in laparoscopic cholecystectomy

ABSTRACT

Evaluate the analgesic effect of single vs multimodel analgesics in postoperative pain in Laparoscopic Cholecystectomy and investigates whether. Prophylactic treatment with multimodel nociceptive blockade will delay the onset of postoperative pain. Decrease analgesic requirement, speed recovery time, and facilitate same. Day discharge in this surgical population. This experimental comparative study was conducted in General Operation Theatre of Nishtar Hospital, Multan during the period from May 2004 to November 2004. Sixty patients were included in the study and divided in 2 equal groups of 30 each using non-probability convenience sampling technique. Group-A-Preoperatively at 45 minutes before induction of anesthesia an intramuscular [IM] bolus injection of Ketorolac 0.5mg/kg was given. Group-B-Preoperatively at 45 minutes before induction of anesthesia, an intramuscular [IM] bolus injection of 0.5mg/kg Ketorolac+2mg/kg body weight of Tramadol [IM]+Local infiltration with 0.5% injection Bupivacaine was done 10 minutes before incision. in Group A, who received Inj. of Ketorolac 0.5 mg/kg, 14 patients [46.7%] had mild pain, 3 patients [10%] had moderate, 6 patients [20%] had severe and 7 patients [23.3%] had no pain. While in group B who received Ketorolac+Tramadol+0.5% of bupivacaine infiltration, the degree of postoperative pain relief I was greater than the Group A in which 14 patients [46.7%] had mild pain, 3 [10%] had moderate and 13 patients [43.3%] had no pain. There was no case having severe postoperative pain in group B. Multimodal analgesia has much more advantage over single analgesia in patients undergoing Laparoscopic Cholecystectomy