Anti-inflammatory and analgesic activity of astragalus hamosus

ABSTRACT

Anti-inflammatory activity of alcoholic and aqueous extracts of the legumes of Astragalus hamosus was determined using rat paw oedema test. At oral doses of 100 mg/kg and 200 mg/kg, the extract inhibited oedema significantly [p<0.01] compared with indomethacin and also showed marked analgesic activity in mice [p<0.25], compared with acetylsalicylic acid in acetic acid-induced writhing test. Toxicity studies were carried and the extracts did not exhibit any toxicity up to 1 g/kg body weight in experimental animals