Evaluation of gastric carcinoembryonic antigen in endemic schistosomal hepatosplenomegaly

ABSTRACT

In endemic hepatosplenomegaly with histopathologically proved atrophic gastritis, the gastric juice carcinoembryonic antigen [CEA] showed significant increase. Comparing this group of patients with histopathologically proved gastric neoplasia the levels were significantly higher in the later group. The level of [CEA] was only increased in 75% of cases with endemic hepatosplenomegaly and atrophic gastritis opposite to 100% of cases with gastric neoplasia. The level of serum [CEA] was also studied in patients and control groups. In patients with endemic hepatosplenomegaly and atrophic gastritis the level was insignificantly higher than the control group and significantly lower than the group with gastric neoplasia