Activity of urinary enzymes in Iranian dromedary camels

ABSTRACT

Determination of the reference values of aspartateaminotransferase [AST], alanine aminotransferase [ALT],alkaline phosphatase [ALP], lactate dehydrogenase [LDH] and gamma glutamyltransferase [GOT] in the urine ofclinically healthy Iranian dromedary camels. Descriptive study. Fifty clinically healthy adult camels [Camelus dromedaries].Urine samples were collected from fiftyclinically healthy adult camels in identical nutritional andmanagernental conditions.Urine specimens werelyophilized and the activity of AST, ALT, ALP, LDH andGOT was measured by routine colorimetric methods. Also,urinalysis and measurement of urine creatinine wereperformed. The data were analysed by analysis ofVariance [ANOVA], Duncan's multiple range test andregression analysis. LDH and GGT showed the highest and the lowestactivity of urinary enzymes were related to LDH and GGT,respectively. Urine pH was alkaline. The concentration ofcreatinine in the urine of Iranian camels was relativelyhigh. According to urinalysis, the urine of Iranian camelswas normal. Significant positive correlations wereobserved between GGT activity and urine creatinine [P<0.05; r=0.26] and ALT activity and specific gravity [P<0.05; r=0.27], respectively. The activity of AST, ALT, ALP, LDH andGGT in the urine of Iranian camels can be used as indicesfor diagnosing renal disorders