Frequency of live births in patients with unexplained recurrent abortions treated with low molecular weight heparin and aspirin

ABSTRACT

To determine the frequency of live birth in patients with unexplained recurrent abortions treated with low molecular weight heparin and aspirin. Descriptive study. This study was carried out at Department of Obstetrics and Gynaecology, Unit-Ill,Nishtar Medical College and Hospital, Multan from 01.01.2014 to 31.12.2014. Sixty women with past history of two or more previous unexplained recurrent abortions who received low-molecular weight heparin [LMWH] and low dose aspirin [LDA] were included in the study and followed subsequently for the pregnancy outcome in the form of live birth measure. The age range between 20 to 40 years with mean 32.38 +/- 3.64 years. A total of sixty patients were studied with a 58.3% patients were belong to age group of 31-35 years. Previous abortion percentage was 36.7% with 2 abortions while 63.3% with 3 abortions with mean 2.63 +/- 0.49 abortions. Live birth was recorded in 51 out of 60 patients with percentage of 85%. An enhancement in the live-birth rate was observed after low-molecular weight heparin [LMWH] and low dose aspirin [LDA] administration, in patient with 2 or more consecutive unexplained recurrent abortions