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Plasma cell leukemia: clinicopathologic, immunophenotypic and cytogenetic characteristics of 4 cases
Hematology, Oncology and Stem Cell Therapy. 2015; 8 (2): 71-77
in English | IMEMR | ID: emr-166933
ABSTRACT
Plasma cell leukemia [PCL] is a rare hematologic malignancy with very poor outcome. It is defined by the presence of >2 · 109/L plasma cells or >20% plasmacytosis of the differential white cell count in the peripheral blood. Primary PCL is first diagnosed in the leukemic phase, while secondary PCL corresponds to the leukemic transformation of a previously diagnosed multiple myeloma [MM]. The incidence of PCL ranges between 2-4% of patients with MM and 0.9% of patients with acute leukemia. In this case series, we describe the clinicopathologic, immunophenotypic, and cytogenetic findings of four patients diagnosed with PCL within a ten-year period [2002-2012] at King Faisal Specialist Hospital and Research Centre [General Organization], Riyadh, Saudi Arabia
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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Hematol. Oncol. Stem Cell Ther. Year: 2015

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Index: IMEMR (Eastern Mediterranean) Language: English Journal: Hematol. Oncol. Stem Cell Ther. Year: 2015