[Diffuse pulmonary lymphangiomatosis: nterest of the treatment by the interferon alpha. About an observation]

ABSTRACT

Diffuse pulmonary lymphangiomatosis is a rare innate pathology characterized by a multifocal proliferation then a dilation of the lung lymphalic vessels. It can be shown at any age, but especially at the infant essentially by non specific respiratory signs. Diagnosis is histopathological. The purpose of our study is to clarify the interest of the interferon in the treatment of this pathology. One-year-old infant Nasr, hospitalized for investigation of a dyspnea evolving since the age of 4 months. The radiography of the chest under treatment antibiotic without clinical or radiological improvement. An etiological inquiry was begun allowing eliminating most frequent pathologies responsible of interstitial chronicle pneumopathies. A surgical lung biopsy was practiced, ended in a diffuse pulmonary lymphangiomatosis. A treatment with interferon was prescribed. Evolution was favorable with a recession of three years and a half. Interferon would be an effective treatment in the diffuse pulmonary lymphangiomatosis but other studies are necessary to appreciate better its effect in this pathology